Bioscience and Bioengineering

The Laboratory’s biological research program was established in 1963 to study the effects of ionizing radiation on humans. Since then, we helped develop flow sorting and chromosome painting to study DNA and chromosomal damage, participated in the Human Genome Project, and developed sensitive and compact biodetection instruments, many of which have been commercialized.

Today, we work at the interface of biology, engineering, and the physical sciences to address national challenges in biosecurity, chemical security, and human health. Livermore has world-class capabilities in genomics, bioinformatics, bioengineering, implantable systems, select agents, toxicology, and bioanalytical science. The overall focus is on understanding human physiology, host–pathogen interactions, and therapeutic targets relating to exposure to chemical and biological agents or environmental hazards.

We’re also integrating big data and predictive simulation capabilities to develop a new understanding of biological complexity and enable more precise predictions of health risk; accelerate development of countermeasures; develop treatment options; and improve outcomes. For example, we’ve partnered with the National Cancer Institute as part of the Cancer Moonshot to drastically reduce the time to developing a cure for cancer.

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