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General flowchart of the pipeline for building the Centrifuge reference database based on the BLAST nt database. The pipeline requires several weeks of processing on a high-performance computing server with high-memory-per-core ratio and a high-bandwidth, low-latency parallel filesystem.
// S&T Highlights

LLNL researchers are working with the National Center for Biotechnology Information's (NCBI) Nucleotide (nt) database to create a vast repository of DNA sequences from across all known species. 

High explosive LLM-105 before and after a laser-initiated burn inside a diamond anvil cell. Sample mass is ~ 1 microgram. The product is opaque at lower pressures and transparent at higher pressures (lower right panel). Note the increase and decrease in pressure, respectively.
// S&T Highlights

LLNL researchers conducted laser ignition experiments in a diamond anvil cell and employed large scale quantum molecular dynamics simulations to investigate the products of deflagration at high pressures. 

Jennifer Pett-Ridge has been recognized as a fellow of the American Association for the Advancement of Science.
// Recognition

Pett-Ridge is among the 471 scientists, engineers and innovators who have been elected American Association for the Advancement of Science 2024 fellows for their scientifically and socially distinguished achievements throughout their careers.

LLNL senior research scientist Aleksandr Noy was recognized as a 2025 MRS fellow.
// Recognition

Aleksandr Noy, an LLNL senior research scientist, has been named a 2025 fellow of the Materials Research Society (MRS).  

Researchers from Lawrence Livermore National Laboratory, in collaboration with other leading institutions, have successfully used an AI-driven platform to preemptively optimize an antibody to neutralize a broad diversity of SARS-CoV-2 variants.
// S&T Highlights

LLNL researchers, in collaboration with other leading institutions, successfully use an AI-driven platform to preemptively optimize an antibody to neutralize a broad diversity of SARS-CoV-2 variants. 

In a leap forward for materials science, a team of researchers from Lawrence Livermore National Laboratory, Harvard University and the University of Pennsylvania has developed a pioneering method of 3D printing cholesteric liquid crystal elastomers, enabling complex, color-changing responsive materials and paving the way for novel applications like smart textiles and advanced robotics.
// S&T Highlights

A multi-institutional team of researchers invent 3D-printed, multi-stable structures capable of changing colors in response to stress, with a goal of combining the unique materials and techniques to help redefine smart materials.

Rick Cross works on the Titan compressor system at the Jupiter Laser Facility. The gratings (rainbow reflection) allow the Titan laser to provide peak power while preserving the optical components of the system.
// S&T Highlights

Since the 1970s, the Janus laser, now part of JLF, has served as an experimental proving ground to LLNL laser and fusion programs and the broader high-energy-density and laser science communities.

A study led by Lawrence Livermore National Laboratory scientists is providing new insights into the complex interactions between proteins and cell membranes, combining detailed molecular simulations and large-scale models. The scientists compared their new dynamic density functional theory (DDFT) model to “ground truth” datasets (labeled “MD”). The DDFT model can be run in a single afternoon on a laptop, instead of the several weeks required to generate the MD data on a supercomputing cluster.
// S&T Highlights

A recent study led by LLNL scientists is offering new insight into modeling complex protein interactions using a combination of detailed molecular simulations and large-scale models. 

LLNL’s rare-earth element biomining research team in their lab, left to right: Yongqin Jiao, Patrick Diep, Ziye Dong, Jeremy Seidel, Gauthier Deblonde, Dan Park and Christina Kang-Yun.
// S&T Highlights

A research collaboration between LLNL and Pennsylvania State University has generated a portfolio of intellectual property (IP), jointly owned by both organizations, that uses bacterial proteins to pick out critical metal ions.  

The latest Big Ideas Lab episode explores LLNL's technology transfer program. Overseen by the Innovation and Partnerships Office, the goal of technology transfer is to bring LLNL breakthroughs to market through research collaborations, technology commercialization and entrepreneurship.
// S&T Highlights

This episode of the Big Ideas Lab podcast takes a deep dive into how the Innovation and Partnerships Office facilitates tech transfer at LLNL and some of the most impactful success stories over the years.